CHOOSE AN EXTENDED HALF-LIFE rFVIII WITH A FAST INFUSION

• Always wash hands and ensure that the area is clean before performing the reconstitution procedures
• Use aseptic technique during the reconstitution procedures
• If the dose requires more than one vial of Esperoct^® per infusion, reconstitute each vial according to the instructions

• Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. The solution should be clear and have no particles. Do not use if particulate matter or discoloration is observed
• Do not administer Esperoct^® in the same tubing or container with other medicinal products
• Administer the Esperoct^® solution immediately. If not used immediately after the reconstitution, store the solution in the vial with the vial adapter and the syringe attached, at room temperature ≤ 86˚F (30˚C) for ≤  4 hours, or stored in a refrigerator at 36˚F to 46˚F (2˚C to 8˚C) for ≤ 24 hours

• The pre-filled diluent syringe is made of glass with an internal tip diameter of 0.037 inches, and is compatible with a standard Luer-lock connector.
• Some needleless connectors for intravenous catheters are incompatible with the glass diluent syringes (for example, certain connectors with an internal spike, such as Clave^®/MicroClave^®, InVision-Plus^®, InVision-Plus CS^®, Invision-Plus Junior^®, Bionector^®), and their use can damage the connector and affect administration. To administer Esperoct^® through incompatible needleless connectors, withdraw the reconstituted product into a standard 10 mL sterile Luer-lock plastic syringe.

Please note, this is not the complete Esperoct^® instructions for use. Please refer to the Instructions for Use included in the Prescribing Information.